Yan, Renhong, Hongwu Qian, Ivan Lukmantara, Mingming Gao, Ximing Du, Nieng Yan, and Hongyuan Yang. (2018) 2018. “Human SEIPIN Binds Anionic Phospholipids”. Dev Cell 47 (2): 248-256.e4. doi:10.1016/j.devcel.2018.09.010. Reference Link
Yan, Nieng. (2013) 2013. “Structural Advances for the Major Facilitator Superfamily (MFS) Transporters”. Trends Biochem Sci 38 (3): 151-9. doi:10.1016/j.tibs.2013.01.003. Reference Link
Wu, Jianping, Zhen Yan, Zhangqiang Li, Xingyang Qian, Shan Lu, Mengqiu Dong, Qiang Zhou, and Nieng Yan. (2016) 2016. “Structure of the Voltage-Gated Calcium Channel Ca(v)1.1 at 3.6 Å Resolution”. Nature 537 (7619): 191-96. doi:10.1038/nature19321. Reference Link
Yan, Nieng, and Yigong Shi. 2005. “Mechanisms of Apoptosis through Structural Biology”. Annu Rev Cell Dev Biol 21: 35-56. doi:10.1146/annurev.cellbio.21.012704.131040. Reference Link
Brown, Andrew, Ngee Kiat Chua, and Nieng Yan. (2019) 2019. “The Shape of Human Squalene Epoxidase Expands the Arsenal Against Cancer”. Nat Commun 10 (1): 888. doi:10.1038/s41467-019-08866-y. Reference Link
Madej, Gregor, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2014) 2014. “Functional Architecture of MFS D-Glucose Transporters”. Proc Natl Acad Sci U S A 111 (7). doi:10.1073/pnas.1400336111. Reference Link
Gong, Xin, Hongwu Qian, Xinhui Zhou, Jianping Wu, Tao Wan, Pingping Cao, Weiyun Huang, et al. (2016) 2016. “Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection”. Cell 165 (6): 1467-78. doi:10.1016/j.cell.2016.05.022. Reference Link
Ke, Meng, Yafei Yuan, Xin Jiang, Nieng Yan, and Haipeng Gong. (2017) 2017. “Molecular Determinants for the Thermodynamic and Functional Divergence of Uniporter GLUT1 and Proton Symporter XylE”. PLoS Comput Biol 13 (6): e1005603. doi:10.1371/journal.pcbi.1005603. Reference Link
Pan, Xiaojing, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Lei Liu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Molecular Basis for Pore Blockade of Human Na Channel Na1.2 by the μ-Conotoxin KIIIA”. Science 363 (6433): 1309-13. doi:10.1126/science.aaw2999. Reference Link
Yin, Ping, Dong Deng, Chuangye Yan, Xiaojing Pan, Jianzhong Jeff Xi, Nieng Yan, and Yigong Shi. (2012) 2012. “Specific DNA-RNA Hybrid Recognition by TAL Effectors”. Cell Rep 2 (4): 707-13. doi:10.1016/j.celrep.2012.09.001. Reference Link
Gong, Xin, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, and Nieng Yan. (2018) 2018. “Structural Basis for the Recognition of Sonic Hedgehog by Human Patched1”. Science 361 (6402). doi:10.1126/science.aas8935. Reference Link
Ren, Ruobing, Xinhui Zhou, Yuan He, Meng Ke, Jianping Wu, Xiaohui Liu, Chuangye Yan, et al. (2015) 2015. “PROTEIN STRUCTURE. Crystal Structure of a Mycobacterial Insig Homolog Provides Insight into How These Sensors Monitor Sterol Levels”. Science 349 (6244): 187-91. doi:10.1126/science.aab1091. Reference Link
Huang, Weiyun, Minhao Liu, Frank Yan, and Nieng Yan. (2017) 2017. “Structure-Based Assessment of Disease-Related Mutations in Human Voltage-Gated Sodium Channels”. Protein Cell 8 (6): 401-38. doi:10.1007/s13238-017-0372-z. Reference Link
Zhang, Xu, Wenlin Ren, Paul DeCaen, Chuangye Yan, Xiao Tao, Lin Tang, Jingjing Wang, et al. (2012) 2012. “Crystal Structure of an Orthologue of the NaChBac Voltage-Gated Sodium Channel”. Nature 486 (7401): 130-4. doi:10.1038/nature11054. Reference Link
Deng, Dong, Pengcheng Sun, Chuangye Yan, Meng Ke, Xin Jiang, Lei Xiong, Wenlin Ren, et al. (2015) 2015. “Molecular Basis of Ligand Recognition and Transport by Glucose Transporters”. Nature 526 (7573): 391-6. doi:10.1038/nature14655. Reference Link
La, Ping, Albert Silva, Zhaoyuan Hou, Haoren Wang, Robert Schnepp, Nieng Yan, Yigong Shi, and Xianxin Hua. (2004) 2004. “Direct Binding of DNA by Tumor Suppressor Menin”. J Biol Chem 279 (47): 49045-54. doi:10.1074/jbc.M409358200. Reference Link
Zhao, Yanyu, Gaoxingyu Huang, Qiurong Wu, Kun Wu, Ruiqi Li, Jianlin Lei, Xiaojing Pan, and Nieng Yan. (2019) 2019. “Cryo-EM Structures of Apo and Antagonist-Bound Human Ca3.1”. Nature 576 (7787): 492-97. doi:10.1038/s41586-019-1801-3. Reference Link
Qian, Hongwu, Pingping Cao, Miaohui Hu, Shuai Gao, Nieng Yan, and Xin Gong. (2019) 2019. “Inhibition of Tetrameric Patched1 by Sonic Hedgehog through an Asymmetric Paradigm”. Nat Commun 10 (1): 2320. doi:10.1038/s41467-019-10234-9. Reference Link
Feng, Liang, David Gell, Suiping Zhou, Lichuan Gu, Yi Kong, Jianqing Li, Min Hu, et al. (2004) 2004. “Molecular Mechanism of AHSP-Mediated Stabilization of Alpha-Hemoglobin”. Cell 119 (5): 629-40. doi:10.1016/j.cell.2004.11.025. Reference Link
Pan, Xiaojing, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, et al. (2018) 2018. “Structure of the Human Voltage-Gated Sodium Channel Na1.4 in Complex With β1”. Science 362 (6412). doi:10.1126/science.aau2486. Reference Link
Sun, Linfeng, Xin Zeng, Chuangye Yan, Xiuyun Sun, Xinqi Gong, Yu Rao, and Nieng Yan. (2012) 2012. “Crystal Structure of a Bacterial Homologue of Glucose Transporters GLUT1-4”. Nature 490 (7420): 361-6. doi:10.1038/nature11524. Reference Link
Shiozaki, Eric, Lichuan Gu, Nieng Yan, and Yigong Shi. (2004) 2004. “Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide: Implications for Signaling”. Mol Cell 14 (3): 405-12. doi:10.1016/s1097-2765(04)00238-2. Reference Link
Gong, Deshun, Ximin Chi, Jinhong Wei, Gewei Zhou, Gaoxingyu Huang, Lin Zhang, Ruiwu Wang, Jianlin Lei, Wayne Chen, and Nieng Yan. (2019) 2019. “Modulation of Cardiac Ryanodine Receptor 2 by Calmodulin”. Nature 572 (7769): 347-51. doi:10.1038/s41586-019-1377-y. Reference Link
Gong, Deshun, Ximin Chi, Kang Ren, Gaoxingyu Huang, Gewei Zhou, Nieng Yan, Jianlin Lei, and Qiang Zhou. (2018) 2018. “Structure of the Human Plasma Membrane Ca-ATPase 1 in Complex With Its Obligatory Subunit Neuroplastin”. Nat Commun 9 (1): 3623. doi:10.1038/s41467-018-06075-7. Reference Link
Wu, Zhuoru, Nieng Yan, Liang Feng, Adam Oberstein, Hanchi Yan, Rosanna Baker, Lichuan Gu, Philip Jeffrey, Sinisa Urban, and Yigong Shi. (2006) 2006. “Structural Analysis of a Rhomboid Family Intramembrane Protease Reveals a Gating Mechanism for Substrate Entry”. Nat Struct Mol Biol 13 (12): 1084-91. doi:10.1038/nsmb1179. Reference Link
Deng, Dong, Chao Xu, Pengcheng Sun, Jianping Wu, Chuangye Yan, Mingxu Hu, and Nieng Yan. (2014) 2014. “Crystal Structure of the Human Glucose Transporter GLUT1”. Nature 510 (7503): 121-5. doi:10.1038/nature13306. Reference Link
Wu, Jianping, Nieng Yan, and Zhen Yan. 2017. “Structure-Function Relationship of the Voltage-Gated Calcium Channel Ca1.1 Complex”. Adv Exp Med Biol 981: 23-39. doi:10.1007/978-3-319-55858-5_2. Reference Link
Deng, Dong, and Nieng Yan. (2016) 2016. “GLUT, SGLT, and SWEET: Structural and Mechanistic Investigations of the Glucose Transporters”. Protein Sci 25 (3): 546-58. doi:10.1002/pro.2858. Reference Link
Deng, Dong, and Nieng Yan. 2018. “Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3”. Methods Mol Biol 1713: 15-29. doi:10.1007/978-1-4939-7507-5_2. Reference Link
Shen, Huaizong, Dongliang Liu, Kun Wu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Structures of Human Na1.7 Channel in Complex With Auxiliary Subunits and Animal Toxins”. Science 363 (6433): 1303-8. doi:10.1126/science.aaw2493. Reference Link
Yu, Xinzhe, Guanghui Yang, Chuangye Yan, Javier Baylon, Jing Jiang, He Fan, Guifeng Lu, et al. (2017) 2017. “Dimeric Structure of the uracil:Proton Symporter UraA Provides Mechanistic Insights into the SLC4 23 26 Transporters”. Cell Res 27 (8): 1020-33. doi:10.1038/cr.2017.83. Reference Link
Yan, Nieng. 2015. “Structural Biology of the Major Facilitator Superfamily Transporters”. Annu Rev Biophys 44: 257-83. doi:10.1146/annurev-biophys-060414-033901. Reference Link
He, Yuan, Kan Wang, and Nieng Yan. (2014) 2014. “The Recombinant Expression Systems for Structure Determination of Eukaryotic Membrane Proteins”. Protein Cell 5 (9): 658-72. doi:10.1007/s13238-014-0086-4. Reference Link
Qian, Hongwu, Xin Zhao, Pingping Cao, Jianlin Lei, Nieng Yan, and Xin Gong. (2017) 2017. “Structure of the Human Lipid Exporter ABCA1”. Cell 169 (7): 1228-1239.e10. doi:10.1016/j.cell.2017.05.020. Reference Link
Fernández-Capetillo, Óscar, Nieng Yan, Jen Dionne, Danielle Bassett, Suchitra Sebastian, Christine Hendon, Hilke Schlichting, and Monya Baker. (2015) 2015. “Hopes for the Year Ahead”. Nature 517 (7532): 111-3. doi:10.1038/nj7532-111a. Reference Link