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Yan, Nieng, Jia-Wei Wu, Jijie Chai, Wenyu Li, and Yigong Shi. (2004) 2004. “Molecular Mechanisms of DrICE Inhibition by DIAP1 and Removal of Inhibition by Reaper, Hid and Grim”. Nat Struct Mol Biol 11 (5): 420-8. doi:10.1038/nsmb764. Reference Link
Gong, Deshun, Ximin Chi, Jinhong Wei, Gewei Zhou, Gaoxingyu Huang, Lin Zhang, Ruiwu Wang, Jianlin Lei, Wayne Chen, and Nieng Yan. (2019) 2019. “Modulation of Cardiac Ryanodine Receptor 2 by Calmodulin”. Nature 572 (7769): 347-51. doi:10.1038/s41586-019-1377-y. Reference Link
Yan, Nieng. (2013) 2013. “Structural Advances for the Major Facilitator Superfamily (MFS) Transporters”. Trends Biochem Sci 38 (3): 151-9. doi:10.1016/j.tibs.2013.01.003. Reference Link
Wu, Zhuoru, Nieng Yan, Liang Feng, Adam Oberstein, Hanchi Yan, Rosanna Baker, Lichuan Gu, Philip Jeffrey, Sinisa Urban, and Yigong Shi. (2006) 2006. “Structural Analysis of a Rhomboid Family Intramembrane Protease Reveals a Gating Mechanism for Substrate Entry”. Nat Struct Mol Biol 13 (12): 1084-91. doi:10.1038/nsmb1179. Reference Link
Deng, Dong, and Nieng Yan. (2016) 2016. “GLUT, SGLT, and SWEET: Structural and Mechanistic Investigations of the Glucose Transporters”. Protein Sci 25 (3): 546-58. doi:10.1002/pro.2858. Reference Link
Yan, Nieng, and Yigong Shi. 2005. “Mechanisms of Apoptosis through Structural Biology”. Annu Rev Cell Dev Biol 21: 35-56. doi:10.1146/annurev.cellbio.21.012704.131040. Reference Link
Yan, Zhen, Qiang Zhou, Lin Wang, Jianping Wu, Yanyu Zhao, Gaoxingyu Huang, Wei Peng, Huaizong Shen, Jianlin Lei, and Nieng Yan. (2017) 2017. “Structure of the Na1.4-β1 Complex from Electric Eel”. Cell 170 (3): 470-482.e11. doi:10.1016/j.cell.2017.06.039. Reference Link
Bai, Xiao-Chen, Zhen Yan, Jianping Wu, Zhangqiang Li, and Nieng Yan. (2016) 2016. “The Central Domain of RyR1 Is the Transducer for Long-Range Allosteric Gating of Channel Opening”. Cell Res 26 (9): 995-1006. doi:10.1038/cr.2016.89. Reference Link
Shen, Huaizong, Dongliang Liu, Kun Wu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Structures of Human Na1.7 Channel in Complex With Auxiliary Subunits and Animal Toxins”. Science 363 (6433): 1303-8. doi:10.1126/science.aaw2493. Reference Link
Yan, Nieng, Yanhui Xu, and Yigong Shi. (2006) 2006. “2:1 Stoichiometry of the CED-4-CED-9 Complex and the Tetrameric CED-4: Insights into the Regulation of CED-3 Activation”. Cell Cycle 5 (1): 31-4. doi:10.4161/cc.5.1.2263. Reference Link
Zhao, Yanyu, Gaoxingyu Huang, Jianping Wu, Qiurong Wu, Shuai Gao, Zhen Yan, Jianlin Lei, and Nieng Yan. (2019) 2019. “Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca Channel”. Cell 177 (6): 1495-1506.e12. doi:10.1016/j.cell.2019.04.043. Reference Link
Gong, Xin, Jingxian Li, Wei Shao, Jianping Wu, Hongwu Qian, Ruobing Ren, Peter Espenshade, and Nieng Yan. (2015) 2015. “Structure of the WD40 Domain of SCAP from Fission Yeast Reveals the Molecular Basis for SREBP Recognition”. Cell Res 25 (4): 401-11. doi:10.1038/cr.2015.32. Reference Link
Yan, Nieng. 2015. “Structural Biology of the Major Facilitator Superfamily Transporters”. Annu Rev Biophys 44: 257-83. doi:10.1146/annurev-biophys-060414-033901. Reference Link
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Shen, Huaizong, Qiang Zhou, Xiaojing Pan, Zhangqiang Li, Jianping Wu, and Nieng Yan. (2017) 2017. “Structure of a Eukaryotic Voltage-Gated Sodium Channel at Near-Atomic Resolution”. Science 355 (6328). doi:10.1126/science.aal4326. Reference Link
Qi, Shiqian, Yuxuan Pang, Qi Hu, Qun Liu, Hua Li, Yulian Zhou, Tianxi He, et al. (2010) 2010. “Crystal Structure of the Caenorhabditis Elegans Apoptosome Reveals an Octameric Assembly of CED-4”. Cell 141 (3): 446-57. doi:10.1016/j.cell.2010.03.017. Reference Link
Wu, Jianping, Zhen Yan, Zhangqiang Li, Xingyang Qian, Shan Lu, Mengqiu Dong, Qiang Zhou, and Nieng Yan. (2016) 2016. “Structure of the Voltage-Gated Calcium Channel Ca(v)1.1 at 3.6 Å Resolution”. Nature 537 (7619): 191-96. doi:10.1038/nature19321. Reference Link
La, Ping, Albert Silva, Zhaoyuan Hou, Haoren Wang, Robert Schnepp, Nieng Yan, Yigong Shi, and Xianxin Hua. (2004) 2004. “Direct Binding of DNA by Tumor Suppressor Menin”. J Biol Chem 279 (47): 49045-54. doi:10.1074/jbc.M409358200. Reference Link
Shen, Huaizong, Zhangqiang Li, Yan Jiang, Xiaojing Pan, Jianping Wu, Ben Cristofori-Armstrong, Jennifer Smith, et al. (2018) 2018. “Structural Basis for the Modulation of Voltage-Gated Sodium Channels by Animal Toxins”. Science 362 (6412). doi:10.1126/science.aau2596. Reference Link
Feng, Liang, David Gell, Suiping Zhou, Lichuan Gu, Yi Kong, Jianqing Li, Min Hu, et al. (2004) 2004. “Molecular Mechanism of AHSP-Mediated Stabilization of Alpha-Hemoglobin”. Cell 119 (5): 629-40. doi:10.1016/j.cell.2004.11.025. Reference Link
Huang, Weiyun, Minhao Liu, Frank Yan, and Nieng Yan. (2017) 2017. “Structure-Based Assessment of Disease-Related Mutations in Human Voltage-Gated Sodium Channels”. Protein Cell 8 (6): 401-38. doi:10.1007/s13238-017-0372-z. Reference Link
Yan, Nieng, Jun Huh, Virgil Schirf, Borries Demeler, Bruce Hay, and Yigong Shi. (2006) 2006. “Structure and Activation Mechanism of the Drosophila Initiator Caspase Dronc”. J Biol Chem 281 (13): 8667-74. doi:10.1074/jbc.M513232200. Reference Link
Wu, Jianping, Zhen Yan, Zhangqiang Li, Chuangye Yan, Shan Lu, Mengqiu Dong, and Nieng Yan. (2015) 2015. “Structure of the Voltage-Gated Calcium Channel Cav1.1 Complex”. Science 350 (6267): aad2395. doi:10.1126/science.aad2395. Reference Link
Chai, Jijie, Nieng Yan, Jun Huh, Jia-Wei Wu, Wenyu Li, Bruce Hay, and Yigong Shi. (2003) 2003. “Molecular Mechanism of Reaper-Grim-Hid-Mediated Suppression of DIAP1-Dependent Dronc Ubiquitination”. Nat Struct Biol 10 (11): 892-8. doi:10.1038/nsb989. Reference Link
Peng, Wei, Huaizong Shen, Jianping Wu, Wenting Guo, Xiaojing Pan, Ruiwu Wang, Wayne Chen, and Nieng Yan. (2016) 2016. “Structural Basis for the Gating Mechanism of the Type 2 Ryanodine Receptor RyR2”. Science 354 (6310). doi:10.1126/science.aah5324. Reference Link
Yan, Nieng, Lichuan Gu, David Kokel, Jijie Chai, Wenyu Li, Aidong Han, Lin Chen, Ding Xue, and Yigong Shi. (2004) 2004. “Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4”. Mol Cell 15 (6): 999-1006. doi:10.1016/j.molcel.2004.08.022. Reference Link
Yan, Zhen, Xiaochen Bai, Chuangye Yan, Jianping Wu, Zhangqiang Li, Tian Xie, Wei Peng, et al. (2015) 2015. “Structure of the Rabbit Ryanodine Receptor RyR1 at Near-Atomic Resolution”. Nature 517 (7532): 50-55. doi:10.1038/nature14063. Reference Link
Huh, Jun, Stephanie Vernooy, Hong Yu, Nieng Yan, Yigong Shi, Ming Guo, and Bruce Hay. (2004) 2004. “Multiple Apoptotic Caspase Cascades Are Required in Nonapoptotic Roles for Drosophila Spermatid Individualization”. PLoS Biol 2 (1): E15. doi:10.1371/journal.pbio.0020015. Reference Link
Wu, Jianping, Nieng Yan, and Zhen Yan. 2017. “Structure-Function Relationship of the Voltage-Gated Calcium Channel Ca1.1 Complex”. Adv Exp Med Biol 981: 23-39. doi:10.1007/978-3-319-55858-5_2. Reference Link
Yan, Nieng, Jijie Chai, Eui Seung Lee, Lichuan Gu, Qun Liu, Jiaqing He, Jia-Wei Wu, et al. (2005) 2005. “Structure of the CED-4-CED-9 Complex Provides Insights into Programmed Cell Death in Caenorhabditis Elegans”. Nature 437 (7060): 831-7. doi:10.1038/nature04002. Reference Link
Chi, Ximin, Deshun Gong, Kang Ren, Gewei Zhou, Gaoxingyu Huang, Jianlin Lei, Qiang Zhou, and Nieng Yan. (2019) 2019. “Molecular Basis for Allosteric Regulation of the Type 2 Ryanodine Receptor Channel Gating by Key Modulators”. Proc Natl Acad Sci U S A 116 (51): 25575-82. doi:10.1073/pnas.1914451116. Reference Link
Yang, Chonglin, Nieng Yan, Jay Parish, Xiaochen Wang, Yigong Shi, and Ding Xue. (2006) 2006. “RNA Aptamers Targeting the Cell Death Inhibitor CED-9 Induce Cell Killing in Caenorhabditis Elegans”. J Biol Chem 281 (14): 9137-44. doi:10.1074/jbc.M511742200. Reference Link