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Gao, Shuai, Xia Yao, and Nieng Yan. 2021. “Structure of Human Cav2. 2 Channel Blocked by the Painkiller Ziconotide”. Nature 596 (7870). Nature Publishing Group: 143–147.

Yan, Renhong, Pingping Cao, Wenqi Song, Yaning Li, Tongtong Wang, Hongwu Qian, Chuangye Yan, and Nieng Yan. 2021. “Structural Basis for Sterol Sensing by Scap and Insig”. Cell Reports 35 (13). Elsevier: 109299.

Li, Zhangqiang, Xueqin Jin, Tong Wu, Gaoxingyu Huang, Kun Wu, Jianlin Lei, Xiaojing Pan, and Nieng Yan. 2021. “Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1. 5 by the Antiarrhythmic Drug Quinidine”. Angewandte Chemie 133 (20). Wiley Online Library: 11575–11581.

Li, Zhangqiang, Xueqin Jin, Tong Wu, Xin Zhao, Weipeng Wang, Jianlin Lei, Xiaojing Pan, and Nieng Yan. 2021. “Structure of Human Nav1. 5 Reveals the Fast Inactivation-Related Segments As a Mutational Hotspot for the Long QT Syndrome”. Proceedings of the National Academy of Sciences 118 (11). National Acad Sciences.

Gao, Shuai, and Nieng Yan. 2021. “Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Cav1. 1 by Dihydropyridine Compounds”. Angewandte Chemie International Edition 60 (6). Wiley Online Library: 3131–3137.

Yao, Xia, Xiao Fan, and Nieng Yan. 2020. “Cryo-EM Analysis of a Membrane Protein Embedded in the Liposome”. Proceedings of the National Academy of Sciences. National Academy of Sciences. doi:10.1073/pnas.2009385117.

Brown, Andrew, Ngee Kiat Chua, and Nieng Yan. (2019) 2019. “The Shape of Human Squalene Epoxidase Expands the Arsenal Against Cancer”. Nat Commun 10 (1): 888. doi:10.1038/s41467-019-08866-y.

Liu, Ying, Huifang Hu, Jia Wang, Qiang Zhou, Peng Wu, Nieng Yan, Hong-Wei Wang, Jia-Wei Wu, and Linfeng Sun. (2019) 2019. “Cryo-EM Structure of L-Fucokinase GDP-Fucose Pyrophosphorylase (FKP) in Bacteroides Fragilis”. Protein Cell 10 (5): 365-69. doi:10.1007/s13238-018-0576-x.

Yan, Nieng, and Yigong Shi. 2005. “Mechanisms of Apoptosis through Structural Biology”. Annu Rev Cell Dev Biol 21: 35-56. doi:10.1146/annurev.cellbio.21.012704.131040.

Zhang, Xu, Mengdie Xia, Yang Li, Huihui Liu, Xin Jiang, Wenlin Ren, Jianping Wu, et al. (2013) 2013. “Analysis of the Selectivity Filter of the Voltage-Gated Sodium Channel Na(v)Rh”. Cell Res 23 (3): 409-22. doi:10.1038/cr.2012.173.

Yan, Nieng, and Yigong Shi. (2007) 2007. “Allosteric Activation of a Bacterial Stress Sensor”. Cell 131 (3): 441-3. doi:10.1016/j.cell.2007.10.021.

Gong, Xin, Hongwu Qian, Xinhui Zhou, Jianping Wu, Tao Wan, Pingping Cao, Weiyun Huang, et al. (2016) 2016. “Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection”. Cell 165 (6): 1467-78. doi:10.1016/j.cell.2016.05.022.

Chi, Ximin, Deshun Gong, Kang Ren, Gewei Zhou, Gaoxingyu Huang, Jianlin Lei, Qiang Zhou, and Nieng Yan. (2019) 2019. “Molecular Basis for Allosteric Regulation of the Type 2 Ryanodine Receptor Channel Gating by Key Modulators”. Proc Natl Acad Sci U S A 116 (51): 25575-82. doi:10.1073/pnas.1914451116.

Jiang, Xin, Irina Smirnova, Vladimir Kasho, Jianping Wu, Kunio Hirata, Meng Ke, Els Pardon, Jan Steyaert, Nieng Yan, and Ronald Kaback. (2016) 2016. “Crystal Structure of a LacY-Nanobody Complex in a Periplasmic-Open Conformation”. Proc Natl Acad Sci U S A 113 (44): 12420-25. doi:10.1073/pnas.1615414113.

Hao, Qi, Ping Yin, Chuangye Yan, Xiaoqiu Yuan, Wenqi Li, Zhiping Zhang, Lei Liu, Jiawei Wang, and Nieng Yan. (2010) 2010. “Functional Mechanism of the Abscisic Acid Agonist Pyrabactin”. J Biol Chem 285 (37): 28946-52. doi:10.1074/jbc.M110.149005.

Feng, Liang, Hanchi Yan, Zhuoru Wu, Nieng Yan, Zhe Wang, Philip Jeffrey, and Yigong Shi. (2007) 2007. “Structure of a Site-2 Protease Family Intramembrane Metalloprotease”. Science 318 (5856): 1608-12. doi:10.1126/science.1150755.

Pan, Xiaojing, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Lei Liu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Molecular Basis for Pore Blockade of Human Na Channel Na1.2 by the μ-Conotoxin KIIIA”. Science 363 (6433): 1309-13. doi:10.1126/science.aaw2999.

Deng, Dong, Chuangye Yan, Xiaojing Pan, Magdy Mahfouz, Jiawei Wang, Jian-Kang Zhu, Yigong Shi, and Nieng Yan. (2012) 2012. “Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors”. Science 335 (6069): 720-3. doi:10.1126/science.1215670.

Wang, Jing, Chuangye Yan, Yini Li, Kunio Hirata, Masaki Yamamoto, Nieng Yan, and Qi Hu. (2014) 2014. “Crystal Structure of a Bacterial Homologue of SWEET Transporters”. Cell Res 24 (12): 1486-9. doi:10.1038/cr.2014.144.

Ren, Ruobing, Xinhui Zhou, Yuan He, Meng Ke, Jianping Wu, Xiaohui Liu, Chuangye Yan, et al. (2015) 2015. “PROTEIN STRUCTURE. Crystal Structure of a Mycobacterial Insig Homolog Provides Insight into How These Sensors Monitor Sterol Levels”. Science 349 (6244): 187-91. doi:10.1126/science.aab1091.

Qian, Hongwu, Xuelan Wu, Ximing Du, Xia Yao, Xin Zhao, Joyce Lee, Hongyuan Yang, and Nieng Yan. 2020. “Structural Basis of Low-PH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2”. Cell, 06/2020. doi:10.1016/j.cell.2020.05.020.

Zhao, Yanyu, Gaoxingyu Huang, Qiurong Wu, Kun Wu, Ruiqi Li, Jianlin Lei, Xiaojing Pan, and Nieng Yan. (2019) 2019. “Cryo-EM Structures of Apo and Antagonist-Bound Human Ca3.1”. Nature 576 (7787): 492-97. doi:10.1038/s41586-019-1801-3.

Shen, Huaizong, Zhangqiang Li, Yan Jiang, Xiaojing Pan, Jianping Wu, Ben Cristofori-Armstrong, Jennifer Smith, et al. (2018) 2018. “Structural Basis for the Modulation of Voltage-Gated Sodium Channels by Animal Toxins”. Science 362 (6412). doi:10.1126/science.aau2596.

Jiang, Xin, Jianping Wu, Meng Ke, Shuo Zhang, Yafei Yuan, Jason Ye Lin, and Nieng Yan. 2019. “Engineered XylE As a Tool for Mechanistic Investigation and Ligand Discovery of the Glucose Transporters GLUTs”. Cell Discov 5: 14. doi:10.1038/s41421-019-0082-1.

Madej, Gregor, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2014) 2014. “Functional Architecture of MFS D-Glucose Transporters”. Proc Natl Acad Sci U S A 111 (7). doi:10.1073/pnas.1400336111.

Li, Quanxiu, Chuangye Yan, Huisha Xu, Zheng Wang, Jiafu Long, Wenqi Li, Jianping Wu, Ping Yin, and Nieng Yan. (2014) 2014. “Examination of the Dimerization States of the Single-Stranded RNA Recognition Protein Pentatricopeptide Repeat 10 (PPR10)”. J Biol Chem 289 (45): 31503-12. doi:10.1074/jbc.M114.575472.

La, Ping, Albert Silva, Zhaoyuan Hou, Haoren Wang, Robert Schnepp, Nieng Yan, Yigong Shi, and Xianxin Hua. (2004) 2004. “Direct Binding of DNA by Tumor Suppressor Menin”. J Biol Chem 279 (47): 49045-54. doi:10.1074/jbc.M409358200.

Pan, Xiaojing, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, et al. (2018) 2018. “Structure of the Human Voltage-Gated Sodium Channel Na1.4 in Complex With β1”. Science 362 (6412). doi:10.1126/science.aau2486.

Yan, Nieng. (2017) 2017. “A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters”. J Mol Biol 429 (17): 2710-25. doi:10.1016/j.jmb.2017.07.009.

Yu, Xinzhe, Guanghui Yang, Chuangye Yan, Javier Baylon, Jing Jiang, He Fan, Guifeng Lu, et al. (2017) 2017. “Dimeric Structure of the uracil:Proton Symporter UraA Provides Mechanistic Insights into the SLC4 23 26 Transporters”. Cell Res 27 (8): 1020-33. doi:10.1038/cr.2017.83.

Ke, Meng, Yafei Yuan, Xin Jiang, Nieng Yan, and Haipeng Gong. (2017) 2017. “Molecular Determinants for the Thermodynamic and Functional Divergence of Uniporter GLUT1 and Proton Symporter XylE”. PLoS Comput Biol 13 (6): e1005603. doi:10.1371/journal.pcbi.1005603.

Li, Wenqi, Li Wang, Xinlei Sheng, Chuangye Yan, Rui Zhou, Jing Hang, Ping Yin, and Nieng Yan. (2013) 2013. “Molecular Basis for the Selective and ABA-Independent Inhibition of PP2CA by PYL13”. Cell Res 23 (12): 1369-79. doi:10.1038/cr.2013.143.

Feng, Liang, David Gell, Suiping Zhou, Lichuan Gu, Yi Kong, Jianqing Li, Min Hu, et al. (2004) 2004. “Molecular Mechanism of AHSP-Mediated Stabilization of Alpha-Hemoglobin”. Cell 119 (5): 629-40. doi:10.1016/j.cell.2004.11.025.

Gong, Deshun, Ximin Chi, Jinhong Wei, Gewei Zhou, Gaoxingyu Huang, Lin Zhang, Ruiwu Wang, Jianlin Lei, Wayne Chen, and Nieng Yan. (2019) 2019. “Modulation of Cardiac Ryanodine Receptor 2 by Calmodulin”. Nature 572 (7769): 347-51. doi:10.1038/s41586-019-1377-y.

Gong, Xin, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, and Nieng Yan. (2018) 2018. “Structural Basis for the Recognition of Sonic Hedgehog by Human Patched1”. Science 361 (6402). doi:10.1126/science.aas8935.

Yin, Ping, Quanxiu Li, Chuangye Yan, Ying Liu, Junjie Liu, Feng Yu, Zheng Wang, et al. (2013) 2013. “Structural Basis for the Modular Recognition of Single-Stranded RNA by PPR Proteins”. Nature 504 (7478): 168-71. doi:10.1038/nature12651.

Deng, Dong, Ping Yin, Chuangye Yan, Xiaojing Pan, Xinqi Gong, Shiqian Qi, Tian Xie, et al. (2012) 2012. “Recognition of Methylated DNA by TAL Effectors”. Cell Res 22 (10): 1502-4. doi:10.1038/cr.2012.127.

Dang, Shangyu, Linfeng Sun, Yongjian Huang, Feiran Lu, Yufeng Liu, Haipeng Gong, Jiawei Wang, and Nieng Yan. (2010) 2010. “Structure of a Fucose Transporter in an Outward-Open Conformation”. Nature 467 (7316): 734-8. doi:10.1038/nature09406.

Yan, Nieng, Jun Huh, Virgil Schirf, Borries Demeler, Bruce Hay, and Yigong Shi. (2006) 2006. “Structure and Activation Mechanism of the Drosophila Initiator Caspase Dronc”. J Biol Chem 281 (13): 8667-74. doi:10.1074/jbc.M513232200.

Deng, Dong, Chao Xu, Pengcheng Sun, Jianping Wu, Chuangye Yan, Mingxu Hu, and Nieng Yan. (2014) 2014. “Crystal Structure of the Human Glucose Transporter GLUT1”. Nature 510 (7503): 121-5. doi:10.1038/nature13306.

Huang, Weiyun, Minhao Liu, Frank Yan, and Nieng Yan. (2017) 2017. “Structure-Based Assessment of Disease-Related Mutations in Human Voltage-Gated Sodium Channels”. Protein Cell 8 (6): 401-38. doi:10.1007/s13238-017-0372-z.

Zhang, Juanrong, Wenzhi Mao, Yanhui Ren, Rui-Ning Sun, Nieng Yan, and Haipeng Gong. (2018) 2018. “Simulating the Ion Permeation and Ion Selection for a Eukaryotic Voltage-Gated Sodium Channel NaPaS”. Protein Cell 9 (6): 580-85. doi:10.1007/s13238-018-0522-y.

Gong, Xin, Hongwu Qian, Wei Shao, Jingxian Li, Jianping Wu, Jun-Jie Liu, Wenqi Li, Hong-Wei Wang, Peter Espenshade, and Nieng Yan. (2016) 2016. “Complex Structure of the Fission Yeast SREBP-SCAP Binding Domains Reveals an Oligomeric Organization”. Cell Res 26 (11): 1197-1211. doi:10.1038/cr.2016.123.

Xia, Mengdie, Huihui Liu, Yang Li, Nieng Yan, and Haipeng Gong. (2013) 2013. “The Mechanism of Na⁺ K⁺ Selectivity in Mammalian Voltage-Gated Sodium Channels Based on Molecular Dynamics Simulation”. Biophys J 104 (11): 2401-9. doi:10.1016/j.bpj.2013.04.035.

Chai, Jijie, Nieng Yan, Jun Huh, Jia-Wei Wu, Wenyu Li, Bruce Hay, and Yigong Shi. (2003) 2003. “Molecular Mechanism of Reaper-Grim-Hid-Mediated Suppression of DIAP1-Dependent Dronc Ubiquitination”. Nat Struct Biol 10 (11): 892-8. doi:10.1038/nsb989.

Deng, Dong, and Nieng Yan. (2016) 2016. “GLUT, SGLT, and SWEET: Structural and Mechanistic Investigations of the Glucose Transporters”. Protein Sci 25 (3): 546-58. doi:10.1002/pro.2858.

Deng, Dong, Pengcheng Sun, Chuangye Yan, Meng Ke, Xin Jiang, Lei Xiong, Wenlin Ren, et al. (2015) 2015. “Molecular Basis of Ligand Recognition and Transport by Glucose Transporters”. Nature 526 (7573): 391-6. doi:10.1038/nature14655.

Han, Yimo, Xiao Fan, Haozhe Wang, Fang Zhao, Christopher Tully, Jing Kong, Nan Yao, and Nieng Yan. (2020) 2020. “High-Yield Monolayer Graphene Grids for Near-Atomic Resolution Cryoelectron Microscopy”. Proc Natl Acad Sci U S A 117 (2): 1009-14. doi:10.1073/pnas.1919114117.

Madej, Gregor, Shangyu Dang, Nieng Yan, and Ronald Kaback. (2013) 2013. “Evolutionary Mix-and-Match With MFS Transporters”. Proc Natl Acad Sci U S A 110 (15): 5870-4. doi:10.1073/pnas.1303538110.