Deng, Dong, Pengcheng Sun, Chuangye Yan, Meng Ke, Xin Jiang, Lei Xiong, Wenlin Ren, et al. (2015) 2015. “Molecular Basis of Ligand Recognition and Transport by Glucose Transporters”. Nature 526 (7573): 391-6. doi:10.1038/nature14655. Reference Link
Zhang, Xu, Wenlin Ren, Paul DeCaen, Chuangye Yan, Xiao Tao, Lin Tang, Jingjing Wang, et al. (2012) 2012. “Crystal Structure of an Orthologue of the NaChBac Voltage-Gated Sodium Channel”. Nature 486 (7401): 130-4. doi:10.1038/nature11054. Reference Link
Sun, Linfeng, Xin Zeng, Chuangye Yan, Xiuyun Sun, Xinqi Gong, Yu Rao, and Nieng Yan. (2012) 2012. “Crystal Structure of a Bacterial Homologue of Glucose Transporters GLUT1-4”. Nature 490 (7420): 361-6. doi:10.1038/nature11524. Reference Link
Feng, Liang, Hanchi Yan, Zhuoru Wu, Nieng Yan, Zhe Wang, Philip Jeffrey, and Yigong Shi. (2007) 2007. “Structure of a Site-2 Protease Family Intramembrane Metalloprotease”. Science 318 (5856): 1608-12. doi:10.1126/science.1150755. Reference Link
Gong, Deshun, Ximin Chi, Kang Ren, Gaoxingyu Huang, Gewei Zhou, Nieng Yan, Jianlin Lei, and Qiang Zhou. (2018) 2018. “Structure of the Human Plasma Membrane Ca-ATPase 1 in Complex With Its Obligatory Subunit Neuroplastin”. Nat Commun 9 (1): 3623. doi:10.1038/s41467-018-06075-7. Reference Link
Yan, Nieng, Jun Huh, Virgil Schirf, Borries Demeler, Bruce Hay, and Yigong Shi. (2006) 2006. “Structure and Activation Mechanism of the Drosophila Initiator Caspase Dronc”. J Biol Chem 281 (13): 8667-74. doi:10.1074/jbc.M513232200. Reference Link
Deng, Dong, and Nieng Yan. 2018. “Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3”. Methods Mol Biol 1713: 15-29. doi:10.1007/978-1-4939-7507-5_2. Reference Link
Yan, Nieng, Lichuan Gu, David Kokel, Jijie Chai, Wenyu Li, Aidong Han, Lin Chen, Ding Xue, and Yigong Shi. (2004) 2004. “Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4”. Mol Cell 15 (6): 999-1006. doi:10.1016/j.molcel.2004.08.022. Reference Link
Deng, Dong, Chuangye Yan, Xiaojing Pan, Magdy Mahfouz, Jiawei Wang, Jian-Kang Zhu, Yigong Shi, and Nieng Yan. (2012) 2012. “Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors”. Science 335 (6069): 720-3. doi:10.1126/science.1215670. Reference Link
Shiozaki, Eric, Lichuan Gu, Nieng Yan, and Yigong Shi. (2004) 2004. “Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide: Implications for Signaling”. Mol Cell 14 (3): 405-12. doi:10.1016/s1097-2765(04)00238-2. Reference Link
Zhang, Juanrong, Wenzhi Mao, Yanhui Ren, Rui-Ning Sun, Nieng Yan, and Haipeng Gong. (2018) 2018. “Simulating the Ion Permeation and Ion Selection for a Eukaryotic Voltage-Gated Sodium Channel NaPaS”. Protein Cell 9 (6): 580-85. doi:10.1007/s13238-018-0522-y. Reference Link
Yan, Nieng, Jia-Wei Wu, Jijie Chai, Wenyu Li, and Yigong Shi. (2004) 2004. “Molecular Mechanisms of DrICE Inhibition by DIAP1 and Removal of Inhibition by Reaper, Hid and Grim”. Nat Struct Mol Biol 11 (5): 420-8. doi:10.1038/nsmb764. Reference Link
Yan, Nieng. (2013) 2013. “Structural Advances for the Major Facilitator Superfamily (MFS) Transporters”. Trends Biochem Sci 38 (3): 151-9. doi:10.1016/j.tibs.2013.01.003. Reference Link
Jiang, Xin, Irina Smirnova, Vladimir Kasho, Jianping Wu, Kunio Hirata, Meng Ke, Els Pardon, Jan Steyaert, Nieng Yan, and Ronald Kaback. (2016) 2016. “Crystal Structure of a LacY-Nanobody Complex in a Periplasmic-Open Conformation”. Proc Natl Acad Sci U S A 113 (44): 12420-25. doi:10.1073/pnas.1615414113. Reference Link
Zhao, Yanyu, Gaoxingyu Huang, Qiurong Wu, Kun Wu, Ruiqi Li, Jianlin Lei, Xiaojing Pan, and Nieng Yan. (2019) 2019. “Cryo-EM Structures of Apo and Antagonist-Bound Human Ca3.1”. Nature 576 (7787): 492-97. doi:10.1038/s41586-019-1801-3. Reference Link
Wang, Jing, Chuangye Yan, Yini Li, Kunio Hirata, Masaki Yamamoto, Nieng Yan, and Qi Hu. (2014) 2014. “Crystal Structure of a Bacterial Homologue of SWEET Transporters”. Cell Res 24 (12): 1486-9. doi:10.1038/cr.2014.144. Reference Link
Deng, Dong, and Nieng Yan. (2016) 2016. “GLUT, SGLT, and SWEET: Structural and Mechanistic Investigations of the Glucose Transporters”. Protein Sci 25 (3): 546-58. doi:10.1002/pro.2858. Reference Link
Madej, Gregor, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2014) 2014. “Functional Architecture of MFS D-Glucose Transporters”. Proc Natl Acad Sci U S A 111 (7). doi:10.1073/pnas.1400336111. Reference Link
Shen, Huaizong, Dongliang Liu, Kun Wu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Structures of Human Na1.7 Channel in Complex With Auxiliary Subunits and Animal Toxins”. Science 363 (6433): 1303-8. doi:10.1126/science.aaw2493. Reference Link
Ke, Meng, Yafei Yuan, Xin Jiang, Nieng Yan, and Haipeng Gong. (2017) 2017. “Molecular Determinants for the Thermodynamic and Functional Divergence of Uniporter GLUT1 and Proton Symporter XylE”. PLoS Comput Biol 13 (6): e1005603. doi:10.1371/journal.pcbi.1005603. Reference Link
Wu, Jianping, Zhen Yan, Zhangqiang Li, Xingyang Qian, Shan Lu, Mengqiu Dong, Qiang Zhou, and Nieng Yan. (2016) 2016. “Structure of the Voltage-Gated Calcium Channel Ca(v)1.1 at 3.6 Å Resolution”. Nature 537 (7619): 191-96. doi:10.1038/nature19321. Reference Link
Madej, Gregor, Shangyu Dang, Nieng Yan, and Ronald Kaback. (2013) 2013. “Evolutionary Mix-and-Match With MFS Transporters”. Proc Natl Acad Sci U S A 110 (15): 5870-4. doi:10.1073/pnas.1303538110. Reference Link
Brown, Andrew, Ngee Kiat Chua, and Nieng Yan. (2019) 2019. “The Shape of Human Squalene Epoxidase Expands the Arsenal Against Cancer”. Nat Commun 10 (1): 888. doi:10.1038/s41467-019-08866-y. Reference Link
Gong, Xin, Jingxian Li, Wei Shao, Jianping Wu, Hongwu Qian, Ruobing Ren, Peter Espenshade, and Nieng Yan. (2015) 2015. “Structure of the WD40 Domain of SCAP from Fission Yeast Reveals the Molecular Basis for SREBP Recognition”. Cell Res 25 (4): 401-11. doi:10.1038/cr.2015.32. Reference Link
Gong, Xin, Hongwu Qian, Xinhui Zhou, Jianping Wu, Tao Wan, Pingping Cao, Weiyun Huang, et al. (2016) 2016. “Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection”. Cell 165 (6): 1467-78. doi:10.1016/j.cell.2016.05.022. Reference Link
Sugihara, Junichi, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2012) 2012. “Dynamics of the L-Fucose H+ Symporter Revealed by Fluorescence Spectroscopy”. Proc Natl Acad Sci U S A 109 (37): 14847-51. doi:10.1073/pnas.1213445109. Reference Link
Pan, Xiaojing, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Lei Liu, Jianlin Lei, and Nieng Yan. (2019) 2019. “Molecular Basis for Pore Blockade of Human Na Channel Na1.2 by the μ-Conotoxin KIIIA”. Science 363 (6433): 1309-13. doi:10.1126/science.aaw2999. Reference Link
Dang, Shangyu, Linfeng Sun, Yongjian Huang, Feiran Lu, Yufeng Liu, Haipeng Gong, Jiawei Wang, and Nieng Yan. (2010) 2010. “Structure of a Fucose Transporter in an Outward-Open Conformation”. Nature 467 (7316): 734-8. doi:10.1038/nature09406. Reference Link
Yan, Nieng. (2017) 2017. “A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters”. J Mol Biol 429 (17): 2710-25. doi:10.1016/j.jmb.2017.07.009. Reference Link
Xia, Mengdie, Huihui Liu, Yang Li, Nieng Yan, and Haipeng Gong. (2013) 2013. “The Mechanism of Na⁺ K⁺ Selectivity in Mammalian Voltage-Gated Sodium Channels Based on Molecular Dynamics Simulation”. Biophys J 104 (11): 2401-9. doi:10.1016/j.bpj.2013.04.035. Reference Link