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Wu, Zhuoru, Nieng Yan, Liang Feng, Adam Oberstein, Hanchi Yan, Rosanna Baker, Lichuan Gu, Philip Jeffrey, Sinisa Urban, and Yigong Shi. (2006) 2006. “Structural Analysis of a Rhomboid Family Intramembrane Protease Reveals a Gating Mechanism for Substrate Entry”. Nat Struct Mol Biol 13 (12): 1084-91. doi:10.1038/nsmb1179. Reference Link
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Sugihara, Junichi, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2012) 2012. “Dynamics of the L-Fucose H+ Symporter Revealed by Fluorescence Spectroscopy”. Proc Natl Acad Sci U S A 109 (37): 14847-51. doi:10.1073/pnas.1213445109. Reference Link
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Dang, Shangyu, Linfeng Sun, Yongjian Huang, Feiran Lu, Yufeng Liu, Haipeng Gong, Jiawei Wang, and Nieng Yan. (2010) 2010. “Structure of a Fucose Transporter in an Outward-Open Conformation”. Nature 467 (7316): 734-8. doi:10.1038/nature09406. Reference Link
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Zhang, Xu, Wenlin Ren, Paul DeCaen, Chuangye Yan, Xiao Tao, Lin Tang, Jingjing Wang, et al. (2012) 2012. “Crystal Structure of an Orthologue of the NaChBac Voltage-Gated Sodium Channel”. Nature 486 (7401): 130-4. doi:10.1038/nature11054. Reference Link
Qian, Hongwu, Pingping Cao, Miaohui Hu, Shuai Gao, Nieng Yan, and Xin Gong. (2019) 2019. “Inhibition of Tetrameric Patched1 by Sonic Hedgehog through an Asymmetric Paradigm”. Nat Commun 10 (1): 2320. doi:10.1038/s41467-019-10234-9. Reference Link
Qi, Shiqian, Yuxuan Pang, Qi Hu, Qun Liu, Hua Li, Yulian Zhou, Tianxi He, et al. (2010) 2010. “Crystal Structure of the Caenorhabditis Elegans Apoptosome Reveals an Octameric Assembly of CED-4”. Cell 141 (3): 446-57. doi:10.1016/j.cell.2010.03.017. Reference Link
Sun, Linfeng, Xin Zeng, Chuangye Yan, Xiuyun Sun, Xinqi Gong, Yu Rao, and Nieng Yan. (2012) 2012. “Crystal Structure of a Bacterial Homologue of Glucose Transporters GLUT1-4”. Nature 490 (7420): 361-6. doi:10.1038/nature11524. Reference Link
Wang, Yi, Yongjian Huang, Jiawei Wang, Chao Cheng, Weijiao Huang, Peilong Lu, Ya-Nan Xu, Pengye Wang, Nieng Yan, and Yigong Shi. (2009) 2009. “Structure of the Formate Transporter FocA Reveals a Pentameric Aquaporin-Like Channel”. Nature 462 (7272): 467-72. doi:10.1038/nature08610. Reference Link
Gong, Deshun, Ximin Chi, Kang Ren, Gaoxingyu Huang, Gewei Zhou, Nieng Yan, Jianlin Lei, and Qiang Zhou. (2018) 2018. “Structure of the Human Plasma Membrane Ca-ATPase 1 in Complex With Its Obligatory Subunit Neuroplastin”. Nat Commun 9 (1): 3623. doi:10.1038/s41467-018-06075-7. Reference Link
Yin, Ping, He Fan, Qi Hao, Xiaoqiu Yuan, Di Wu, Yuxuan Pang, Chuangye Yan, Wenqi Li, Jiawei Wang, and Nieng Yan. (2009) 2009. “Structural Insights into the Mechanism of Abscisic Acid Signaling by PYL Proteins”. Nat Struct Mol Biol 16 (12): 1230-6. doi:10.1038/nsmb.1730. Reference Link
Yan, Zhen, Xiaochen Bai, Chuangye Yan, Jianping Wu, Zhangqiang Li, Tian Xie, Wei Peng, et al. (2015) 2015. “Structure of the Rabbit Ryanodine Receptor RyR1 at Near-Atomic Resolution”. Nature 517 (7532): 50-55. doi:10.1038/nature14063. Reference Link
Xie, Tian, Ruobing Ren, Yuan-yuan Zhang, Yuxuan Pang, Chuangye Yan, Xinqi Gong, Yuan He, et al. (2012) 2012. “Molecular Mechanism for Inhibition of a Critical Component in the Arabidopsis Thaliana Abscisic Acid Signal Transduction Pathways, SnRK2.6, by Protein Phosphatase ABI1”. J Biol Chem 287 (1): 794-802. doi:10.1074/jbc.M111.313106. Reference Link
Zhao, Yanyu, Gaoxingyu Huang, Qiurong Wu, Kun Wu, Ruiqi Li, Jianlin Lei, Xiaojing Pan, and Nieng Yan. (2019) 2019. “Cryo-EM Structures of Apo and Antagonist-Bound Human Ca3.1”. Nature 576 (7787): 492-97. doi:10.1038/s41586-019-1801-3. Reference Link
Chi, Ximin, Deshun Gong, Kang Ren, Gewei Zhou, Gaoxingyu Huang, Jianlin Lei, Qiang Zhou, and Nieng Yan. (2019) 2019. “Molecular Basis for Allosteric Regulation of the Type 2 Ryanodine Receptor Channel Gating by Key Modulators”. Proc Natl Acad Sci U S A 116 (51): 25575-82. doi:10.1073/pnas.1914451116. Reference Link
He, Wenrong, Javier Brumos, Hongjiang Li, Yusi Ji, Meng Ke, Xinqi Gong, Qinglong Zeng, et al. (2011) 2011. “A Small-Molecule Screen Identifies L-Kynurenine As a Competitive Inhibitor of TAA1 TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth in Arabidopsis”. Plant Cell 23 (11): 3944-60. doi:10.1105/tpc.111.089029. Reference Link
Gong, Deshun, Ximin Chi, Jinhong Wei, Gewei Zhou, Gaoxingyu Huang, Lin Zhang, Ruiwu Wang, Jianlin Lei, Wayne Chen, and Nieng Yan. (2019) 2019. “Modulation of Cardiac Ryanodine Receptor 2 by Calmodulin”. Nature 572 (7769): 347-51. doi:10.1038/s41586-019-1377-y. Reference Link
Deng, Dong, Chuangye Yan, Xiaojing Pan, Magdy Mahfouz, Jiawei Wang, Jian-Kang Zhu, Yigong Shi, and Nieng Yan. (2012) 2012. “Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors”. Science 335 (6069): 720-3. doi:10.1126/science.1215670. Reference Link
Feng, Liang, David Gell, Suiping Zhou, Lichuan Gu, Yi Kong, Jianqing Li, Min Hu, et al. (2004) 2004. “Molecular Mechanism of AHSP-Mediated Stabilization of Alpha-Hemoglobin”. Cell 119 (5): 629-40. doi:10.1016/j.cell.2004.11.025. Reference Link
Deng, Dong, Chao Xu, Pengcheng Sun, Jianping Wu, Chuangye Yan, Mingxu Hu, and Nieng Yan. (2014) 2014. “Crystal Structure of the Human Glucose Transporter GLUT1”. Nature 510 (7503): 121-5. doi:10.1038/nature13306. Reference Link
Yin, Ping, Quanxiu Li, Chuangye Yan, Ying Liu, Junjie Liu, Feng Yu, Zheng Wang, et al. (2013) 2013. “Structural Basis for the Modular Recognition of Single-Stranded RNA by PPR Proteins”. Nature 504 (7478): 168-71. doi:10.1038/nature12651. Reference Link
Yan, Nieng, Jun Huh, Virgil Schirf, Borries Demeler, Bruce Hay, and Yigong Shi. (2006) 2006. “Structure and Activation Mechanism of the Drosophila Initiator Caspase Dronc”. J Biol Chem 281 (13): 8667-74. doi:10.1074/jbc.M513232200. Reference Link
Deng, Dong, and Nieng Yan. (2016) 2016. “GLUT, SGLT, and SWEET: Structural and Mechanistic Investigations of the Glucose Transporters”. Protein Sci 25 (3): 546-58. doi:10.1002/pro.2858. Reference Link
Yan, Nieng, and Yigong Shi. 2005. “Mechanisms of Apoptosis through Structural Biology”. Annu Rev Cell Dev Biol 21: 35-56. doi:10.1146/annurev.cellbio.21.012704.131040. Reference Link
Yan, Nieng, Lichuan Gu, David Kokel, Jijie Chai, Wenyu Li, Aidong Han, Lin Chen, Ding Xue, and Yigong Shi. (2004) 2004. “Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4”. Mol Cell 15 (6): 999-1006. doi:10.1016/j.molcel.2004.08.022. Reference Link
Yan, Zhen, Qiang Zhou, Lin Wang, Jianping Wu, Yanyu Zhao, Gaoxingyu Huang, Wei Peng, Huaizong Shen, Jianlin Lei, and Nieng Yan. (2017) 2017. “Structure of the Na1.4-β1 Complex from Electric Eel”. Cell 170 (3): 470-482.e11. doi:10.1016/j.cell.2017.06.039. Reference Link
Jiang, Xin, Irina Smirnova, Vladimir Kasho, Jianping Wu, Kunio Hirata, Meng Ke, Els Pardon, Jan Steyaert, Nieng Yan, and Ronald Kaback. (2016) 2016. “Crystal Structure of a LacY-Nanobody Complex in a Periplasmic-Open Conformation”. Proc Natl Acad Sci U S A 113 (44): 12420-25. doi:10.1073/pnas.1615414113. Reference Link
Chai, Jijie, Jia-Wei Wu, Nieng Yan, Joan Massagué, Nikola Pavletich, and Yigong Shi. (2003) 2003. “Features of a Smad3 MH1-DNA Complex. Roles of Water and Zinc in DNA Binding”. J Biol Chem 278 (22): 20327-31. doi:10.1074/jbc.C300134200. Reference Link
Zhao, Yanyu, Gaoxingyu Huang, Jianping Wu, Qiurong Wu, Shuai Gao, Zhen Yan, Jianlin Lei, and Nieng Yan. (2019) 2019. “Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca Channel”. Cell 177 (6): 1495-1506.e12. doi:10.1016/j.cell.2019.04.043. Reference Link
Wang, Jing, Chuangye Yan, Yini Li, Kunio Hirata, Masaki Yamamoto, Nieng Yan, and Qi Hu. (2014) 2014. “Crystal Structure of a Bacterial Homologue of SWEET Transporters”. Cell Res 24 (12): 1486-9. doi:10.1038/cr.2014.144. Reference Link
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Qian, Hongwu, Xin Zhao, Pingping Cao, Jianlin Lei, Nieng Yan, and Xin Gong. (2017) 2017. “Structure of the Human Lipid Exporter ABCA1”. Cell 169 (7): 1228-1239.e10. doi:10.1016/j.cell.2017.05.020. Reference Link
Madej, Gregor, Linfeng Sun, Nieng Yan, and Ronald Kaback. (2014) 2014. “Functional Architecture of MFS D-Glucose Transporters”. Proc Natl Acad Sci U S A 111 (7). doi:10.1073/pnas.1400336111. Reference Link
Shiozaki, Eric, Lichuan Gu, Nieng Yan, and Yigong Shi. (2004) 2004. “Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide: Implications for Signaling”. Mol Cell 14 (3): 405-12. doi:10.1016/s1097-2765(04)00238-2. Reference Link
Wu, Jianping, Zhen Yan, Zhangqiang Li, Xingyang Qian, Shan Lu, Mengqiu Dong, Qiang Zhou, and Nieng Yan. (2016) 2016. “Structure of the Voltage-Gated Calcium Channel Ca(v)1.1 at 3.6 Å Resolution”. Nature 537 (7619): 191-96. doi:10.1038/nature19321. Reference Link
Bai, Xiao-Chen, Zhen Yan, Jianping Wu, Zhangqiang Li, and Nieng Yan. (2016) 2016. “The Central Domain of RyR1 Is the Transducer for Long-Range Allosteric Gating of Channel Opening”. Cell Res 26 (9): 995-1006. doi:10.1038/cr.2016.89. Reference Link
Yan, Nieng, Jia-Wei Wu, Jijie Chai, Wenyu Li, and Yigong Shi. (2004) 2004. “Molecular Mechanisms of DrICE Inhibition by DIAP1 and Removal of Inhibition by Reaper, Hid and Grim”. Nat Struct Mol Biol 11 (5): 420-8. doi:10.1038/nsmb764. Reference Link