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Yan, Renhong, Pingping Cao, Wenqi Song, Yaning Li, Tongtong Wang, Hongwu Qian, Chuangye Yan, and Nieng Yan. 2021. “Structural Basis for Sterol Sensing by Scap and Insig”. Cell Reports 35 (13). Elsevier: 109299. Reference Link
Yan, Renhong, Pingping Cao, Wenqi Song, Hongwu Qian, Ximing Du, Hudson Coates, Xin Zhao, et al. 2021. “A Structure of Human Scap Bound to Insig-2 Suggests How Their Interaction Is Regulated by Sterols”. Science 371 (6533). American Association for the Advancement of Science: eabb2224. Reference Link
Qian, Hongwu, Xin Zhao, Pingping Cao, Jianlin Lei, Nieng Yan, and Xin Gong. (2017) 2017. “Structure of the Human Lipid Exporter ABCA1”. Cell 169 (7): 1228-1239.e10. doi:10.1016/j.cell.2017.05.020. Reference Link
Yan, Renhong, Hongwu Qian, Ivan Lukmantara, Mingming Gao, Ximing Du, Nieng Yan, and Hongyuan Yang. (2018) 2018. “Human SEIPIN Binds Anionic Phospholipids”. Dev Cell 47 (2): 248-256.e4. doi:10.1016/j.devcel.2018.09.010. Reference Link
Gong, Xin, Hongwu Qian, Xinhui Zhou, Jianping Wu, Tao Wan, Pingping Cao, Weiyun Huang, et al. (2016) 2016. “Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection”. Cell 165 (6): 1467-78. doi:10.1016/j.cell.2016.05.022. Reference Link
Gong, Xin, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, and Nieng Yan. (2018) 2018. “Structural Basis for the Recognition of Sonic Hedgehog by Human Patched1”. Science 361 (6402). doi:10.1126/science.aas8935. Reference Link
Qian, Hongwu, Pingping Cao, Miaohui Hu, Shuai Gao, Nieng Yan, and Xin Gong. (2019) 2019. “Inhibition of Tetrameric Patched1 by Sonic Hedgehog through an Asymmetric Paradigm”. Nat Commun 10 (1): 2320. doi:10.1038/s41467-019-10234-9. Reference Link
Wang, Lie, Hongwu Qian, Yin Nian, Yimo Han, Zhenning Ren, Hanzhi Zhang, Liya Hu, et al. (2020) 2020. “Structure and Mechanism of Human Diacylglycerol O-acyltransferase 1”. Nature 581 (7808): 329-32. doi:10.1038/s41586-020-2280-2. Reference Link
Qian, Hongwu, Xin Zhao, Renhong Yan, Xia Yao, Shuai Gao, Xue Sun, Ximing Du, Hongyuan Yang, Catherine CL Wong, and Nieng Yan. (2020) 2020. “Structural Basis for Catalysis and Substrate Specificity of Human ACAT1”. Nature 581 (7808): 333-38. doi:10.1038/s41586-020-2290-0. Reference Link
Gong, Xin, Hongwu Qian, Wei Shao, Jingxian Li, Jianping Wu, Jun-Jie Liu, Wenqi Li, Hong-Wei Wang, Peter Espenshade, and Nieng Yan. (2016) 2016. “Complex Structure of the Fission Yeast SREBP-SCAP Binding Domains Reveals an Oligomeric Organization”. Cell Res 26 (11): 1197-1211. doi:10.1038/cr.2016.123. Reference Link
Gong, Xin, Jingxian Li, Wei Shao, Jianping Wu, Hongwu Qian, Ruobing Ren, Peter Espenshade, and Nieng Yan. (2015) 2015. “Structure of the WD40 Domain of SCAP from Fission Yeast Reveals the Molecular Basis for SREBP Recognition”. Cell Res 25 (4): 401-11. doi:10.1038/cr.2015.32. Reference Link
Qian, Hongwu, Xuelan Wu, Ximing Du, Xia Yao, Xin Zhao, Joyce Lee, Hongyuan Yang, and Nieng Yan. 2020. “Structural Basis of Low-PH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2”. Cell, 06/2020. doi:10.1016/j.cell.2020.05.020. Reference Link